{"product_id":"regenerating-micro-spicules-serum-pdrn-egf-complex","title":"Regenerating Micro-Spicules Serum","description":"\u003cdiv class=\"typology-product-content\"\u003e\n\u003csection class=\"typology-product-tags\"\u003e\u003ch2\u003eThis product is\u003c\/h2\u003e\n\u003cp\u003eMade in France, Vegan, Yuka score 91\/100\u003c\/p\u003e\u003c\/section\u003e\u003csection class=\"typology-content-section typology-content-section--reverse\"\u003e\u003cdiv class=\"typology-content-visual\"\u003e\u003cdiv class=\"typology-content-media-slot\" data-typ-media-key=\"s1-main\"\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"typology-content-copy\"\u003e\n\u003ch2\u003eA63 - Regenerating Micro-Spicules Serum\u003c\/h2\u003e\n\u003cdiv class=\"typology-content-subtitle\"\u003e\u003cp\u003e\u003cb\u003eA non-invasive skin regeneration solution inspired by microneedling, using a vegan micro-spicules technology.\u003c\/b\u003e\u003c\/p\u003e\u003c\/div\u003e\n\u003cdiv class=\"typology-content-items\"\u003e\n\u003cdetails class=\"typology-content-item\" open\u003e\u003csummary\u003e\u003cspan\u003eA serum particularly suited to mature skin\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-content-item-body\"\u003e\n\u003cp\u003eThe Regenerating Micro-Spicules Serum A63 is suitable for all skin types, except sensitive or reactive skin. It is particularly well-suited for mature skin, dull skin, or skin with texture irregularities or uneven pigmentation.\u003c\/p\u003e\n\u003cp\u003eWe advise against use on skin prone to chronic redness or presenting open lesions.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-content-item\"\u003e\u003csummary\u003e\u003cspan\u003e150,000 vegan micro-spicules\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-content-item-body\"\u003e\n\u003cp\u003eThis serum contains 150,000 micro-spicules per gram of product, fine microstructures of mineral origin. Upon application, they create superficial, transient, and painless micro-channels at the surface of the epidermis. \u003c\/p\u003e\n\u003cp\u003eThis mechanical stimulation bypasses the skin barrier to optimize the penetration of high-molecular-weight active ingredients, such as EGF-β or PDRN, which would struggle to diffuse through the skin barrier if used alone.\u003c\/p\u003e\n\u003cp\u003eAt the same time, this mechanical stimulation activates the skin's natural renewal mechanisms and contributes to collagen and elastin synthesis.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-content-item\"\u003e\u003csummary\u003e\u003cspan\u003eFluid, lightweight texture\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-content-item-body\"\u003e\n\u003cp\u003eThe Regenerating Micro-Spicules Serum A63 is a fluid, lightweight emulsion that absorbs quickly into the skin.\u003c\/p\u003e\n\u003cp\u003eApplication may cause a mild tingling sensation; this is a normal, temporary reaction to the skin's response upon contact with the micro-spicules.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-content-item\"\u003e\u003csummary\u003e\u003cspan\u003eA formula enriched with regenerating and firming active ingredients\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-content-item-body\"\u003e\n\u003cp\u003e\u003cb\u003eEGF-β [\u003c\/b\u003e\u003cb\u003e7 kDa\u003c\/b\u003e\u003cb\u003e] 2%:\u003c\/b\u003e\u003cbr\u003eEGF-β is a biomimetic growth factor derived through plant biotechnology. Produced by Nicotiana benthamiana plants, it replicates the structure and activity of the growth factor naturally present in skin. \u003c\/p\u003e\n\u003cp\u003eEGF-β activates fibroblast and keratinocyte receptors, promoting cell renewal and the synthesis of extracellular matrix components. \u003c\/p\u003e\n\u003cp\u003eIt also helps increase the thickness of the epidermis by stimulating keratinocyte renewal and migration. Better supported, the dermis can then perform its mechanical role more effectively, improving skin firmness, elasticity, and density.\u003cbr\u003e\u003cbr\u003e\u003cb\u003ePDRN [\u003c\/b\u003e\u003cb\u003e32,5 - 65 kDa\u003c\/b\u003e\u003cb\u003e] 1%:\u003c\/b\u003e\u003cbr\u003eThe PDRN used in this serum consists of DNA fragments obtained through biotechnology from Lactobacillus rhamnosus strains. It offers a vegan alternative to PDRN traditionally derived from salmon [130 - 520 kDa]. \u003c\/p\u003e\n\u003cp\u003eThis active ingredient supports skin regeneration and activates the synthesis of structural proteins in the extracellular matrix by fibroblasts, improving skin suppleness and elasticity. \u003c\/p\u003e\n\u003cp\u003ePDRN also has anti-inflammatory properties. It limits the production of pro-inflammatory cytokines, such as TNF-α, IL-1β, and IL-6, while increasing the synthesis of anti-inflammatory cytokines, such as IL-10 — promoting an environment more conducive to skin regeneration and new tissue formation.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-content-item\"\u003e\u003csummary\u003e\u003cspan\u003e91% found their skin regenerated\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-content-item-body\"\u003e\n\u003cp\u003eThe efficacy of the Regenerating Micro-Spicules Serum A63 was assessed after 28 days of use in a consumer use test.\u003c\/p\u003e\n\u003cp\u003e\u003cu\u003eProven efficacy:\u003c\/u\u003e\u003c\/p\u003e\n\u003cul\u003e\n\u003cli\u003e\u003cp\u003e\u003cb\u003e100%\u003c\/b\u003e find that the product improves skin radiance*\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003cb\u003e96%\u003c\/b\u003e find that the product improves skin texture*\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003cb\u003e91%\u003c\/b\u003e find their skin feels smoother*\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003cb\u003e91%\u003c\/b\u003e find that skin feels regenerated*\u003c\/p\u003e\u003c\/li\u003e\n\u003cli\u003e\u003cp\u003e\u003cb\u003e73%\u003c\/b\u003e find that wrinkles appear less deep*\u003c\/p\u003e\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp\u003e\u003ci\u003e*Usage test conducted on 23 volunteers with various skin types, used twice a week for 28 days.\u003c\/i\u003e\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-content-item\"\u003e\u003csummary\u003e\u003cspan\u003eRecyclable glass bottle\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-content-item-body\"\u003e\n\u003cp\u003eProduct composed of a glass bottle, a glass pipette, and a recyclable Polypropylene (PP) ring.\u003c\/p\u003e\n\u003cp\u003eThe nitrile nipple should be disposed of in the household waste bin.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-content-item\"\u003e\u003csummary\u003e\u003cspan\u003eIngredients\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-content-item-body\"\u003e\n\u003cp\u003e20 ingredients. \u003cbr\u003e95% naturally derived.\u003c\/p\u003e\n\u003cp\u003eAqua (Water), Propanediol, Coco-Caprylate\/Caprate, Calcium Aluminum Borosilicate, Caprylic\/Capric Triglyceride, 1,2-Hexanediol, Glyceryl Stearate Citrate, Glycerin, Sodium DNA, Arginine\/Lysine Polypeptide, Lactobacillus Ferment, Sphingomonas Ferment Extract, Tocopherol, Glyceryl Stearate, Xanthan Gum, Glyceryl Caprylate, Ethylhexylglycerin, Benzyl Alcohol, Dehydroacetic Acid, Sodium Hydroxide.\u003c\/p\u003e\n\u003cp\u003eThe ingredient lists for our products are updated on a regular basis. Before using any of our products, we encourage you to read the ingredient list on the packaging to confirm that the ingredients are suitable for your personal use.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\u003c\/section\u003e\u003csection class=\"typology-faq-section\"\u003e\u003cdiv class=\"typology-content-visual typology-faq-visual\"\u003e\u003cdiv class=\"typology-content-media-slot\" data-typ-media-key=\"s2-faq\"\u003e\u003c\/div\u003e\u003c\/div\u003e\n\u003cdiv class=\"typology-faq-copy\"\u003e\n\u003cdiv class=\"typology-faq-items\"\u003e\n\u003cdiv class=\"typology-faq-page\" data-faq-page=\"1\"\u003e\n\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eHow to apply the Regenerating Micro-Spicules Serum A63?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\n\u003cp\u003eApply three to four drops to the entire face, evening only, before your moisturizer. Use once to twice a week.\u003c\/p\u003e\n\u003cp\u003eAvoid contact with mouth and area around the eyes. If contact occurs, rinse thoroughly with water. Do not apply to sensitive, inflamed or damaged skin, or to skin with lesions.\u003c\/p\u003e\n\u003cp\u003eThe serum may cause a mild tingling sensation upon application. This is a normal and temporary reaction, caused by the presence of micro-spicules in the formula.\u003c\/p\u003e\n\u003cp\u003eThis product is not recommended for sensitive skin.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eWho is the Regenerating Micro-Spicules Serum A63 for?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\n\u003cp\u003eThe Regenerating Micro-Spicules Serum A63 is particularly suited for mature skin, as well as dull skin or skin with texture irregularities or uneven pigmentation.\u003c\/p\u003e\n\u003cp\u003eWe do not recommend it for sensitive or reactive skin.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eIs the Regenerating Micro-Spicules Serum A63 suitable for pregnant or breastfeeding women?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eThe Regenerating Micro-Spicules Serum A63 is not contraindicated for pregnant or breastfeeding women. If it were, this would be clearly stated in the usage precautions on the product page. The complete list of ingredients to avoid during pregnancy and breastfeeding is available here:\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eIs it normal to feel a tingling sensation when applying?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eMild, temporary tingling upon application is normal. These sensations are caused by the skin's response to 150,000 micro-spicules per gram of product and the formation of superficial micro-channels at the skin's surface.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eDoes the Regenerating Micro-Spicules Serum A63 replace a professional microneedling session?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eThis is a non-invasive solution inspired by aesthetic medicine protocols, specifically calibrated for home use and accessible to those looking to get started with this technology.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eIs the Regenerating Micro-Spicules Serum A63 photosensitizing?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\n\u003cp\u003eThe Regenerating Micro-Spicule Serum A63 contains no photosensitizing ingredients. We recommend applying it in the evening to support the skin's natural cell renewal process overnight.\u003c\/p\u003e\n\u003cp\u003eWe always recommend applying a daily sunscreen during the day to help limit skin aging, regardless of the treatment used.\u003c\/p\u003e\n\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eCan I use the Regenerating Micro-Spicules Serum A63 every night?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eNo. The Regenerating Micro-Spicules Serum A63 is designed for use once to twice a week, in the evening only. Using it more frequently than recommended does not improve results and may cause unnecessary irritation, as the skin needs time to recover between applications.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eIs the Regenerating Micro-Spicules Serum A63 suitable for use in summer?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eYes, the Regenerating Micro-Spicules Serum A63 can be used year-round. Since it is applied in the evening and contains no photosensitizing ingredients, seasonal changes do not affect its suitability. As always, applying a daily sunscreen in the morning is recommended, regardless of the treatment used.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"typology-faq-page\" data-faq-page=\"2\" hidden\u003e\n\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eShould I apply my moisturizer immediately after the Regenerating Micro-Spicules Serum A63, or wait?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eApply your moisturizer after the Regenerating Micro-Spicules Serum A63 has fully absorbed into the skin. Given its fluid, lightweight texture, absorption is quick. Layering a moisturizer on top helps support the skin's recovery overnight.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eWhen can I expect to see results with the Regenerating Micro-Spicules Serum A63?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eThe consumer use test was conducted over 28 days, with application twice a week. Results such as improved skin texture, radiance, and smoothness were observed within that timeframe. Individual results will vary depending on skin type and consistency of use.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eCan I use the Regenerating Micro-Spicules Serum A63 if I have occasional breakouts, but my skin is not generally sensitive?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eAvoid applying the Regenerating Micro-Spicules Serum A63 directly to active breakouts, open lesions, or inflamed areas. If your skin is not generally sensitive or reactive and the breakouts are localized, you may apply the serum to unaffected areas, taking care to avoid any compromised skin.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eCan I travel with the Regenerating Micro-Spicules Serum A63?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eThe Regenerating Micro-Spicules Serum A63 comes in a glass bottle with a pipette. When traveling, ensure the bottle is stored upright and protected from impact. If traveling by air, check that the volume complies with carry-on liquid restrictions in your destination country.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eCan I use the Regenerating Micro-Spicules Serum A63 on the same evenings as other exfoliating treatments?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eWe recommend against combining the Regenerating Micro-Spicules Serum A63 with other exfoliating treatments on the same evening. The micro-spicules already create superficial micro-channels at the skin's surface; adding a chemical or physical exfoliant the same night may over-stimulate the skin and compromise its barrier.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eHow long does one bottle of the Regenerating Micro-Spicules Serum A63 typically last?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eAt the recommended frequency of once to twice a week, using three to four drops per application, one bottle provides several months of use. Exact duration will vary slightly depending on application habits.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\u003cdetails class=\"typology-faq-item\"\u003e\u003csummary\u003e\u003cspan\u003eHow should I store the Regenerating Micro-Spicules Serum A63?\u003c\/span\u003e\u003cspan class=\"typology-content-toggle\" aria-hidden=\"true\"\u003e\u003c\/span\u003e\u003c\/summary\u003e\u003cdiv class=\"typology-faq-item-body\"\u003e\u003cdiv class=\"typology-faq-answer\"\u003e\u003cp\u003eStore the Regenerating Micro-Spicules Serum A63 at room temperature, away from direct sunlight and heat. The glass bottle protects the formula from light exposure, but avoiding extreme temperature fluctuations helps preserve the stability of the active ingredients.\u003c\/p\u003e\u003c\/div\u003e\u003c\/div\u003e\u003c\/details\u003e\n\u003c\/div\u003e\n\u003c\/div\u003e\n\u003cnav class=\"typology-faq-pagination\" aria-label=\"FAQ pages\"\u003e\u003cbutton type=\"button\" data-faq-page-button=\"1\" class=\"is-active\" aria-current=\"page\"\u003e01\u003c\/button\u003e\u003cbutton type=\"button\" data-faq-page-button=\"2\"\u003e02\u003c\/button\u003e\u003c\/nav\u003e\n\u003c\/div\u003e\u003c\/section\u003e\n\u003c\/div\u003e","brand":"Typology Paris","offers":[{"title":"1 floz","offer_id":45889848410186,"sku":"LAB1035-30ML-SG","price":31.8,"currency_code":"USD","in_stock":true},{"title":"0.50 floz","offer_id":45889848442954,"sku":"LAB1035-15ML-SG","price":18.2,"currency_code":"USD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0727\/6216\/3274\/files\/packshot_3d_a63.jpg?v=1789981412","url":"https:\/\/us-typology.com\/products\/regenerating-micro-spicules-serum-pdrn-egf-complex","provider":"Typology","version":"1.0","type":"link"}